A purine base
Related Products
Isomer(s)
21703Isoguanine
Labeled Version(s)
41180Guanine-15N5
Technical Support & Resources

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Guanine

Item No. 34248

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-1,9-dihydro-6H-purin-6-one
CAS Number
73-40-5
Molecular Formula
C5H5N5O
Formula Weight
151.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Aqueous acid: SolubleWater: Sparingly soluble
λmax
248 nm
SMILES
O=C1N=C(NC2=C1NC=N2)N
InChi Code
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
InChi Key
UYTPUPDQBNUYGX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 g

    $35

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    100 g

    $65

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    250 g

    $152

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    Product Description

    Guanine is a purine base.1 It forms complementary base pairs with the pyrimidine cytosine in DNA and RNA. Guanine can be linked to ribose via a β-N9-glycosidic bond to form the purine nucleoside guanosine (Item No. 27702), which can be phosphorylated to guanine-based purines that have numerous roles in intracellular signal transduction.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Biochemistry. (2002).

    2. Devereaux, Z.J., He, C.C., Zhu, Y., et al. Structures and relative glycosidic bond stabilities of protonated 2'-fluoro-substituted purine nucleosides. J. Am. Soc. Mass Spectrom. 30(8), 1521-1536 (2019).

    3. Di Liberto, V., Mudò, G., Garozzo, R., et al. The guanine-based purinergic system: The tale of an orphan neuromodulation. Front. Pharmacol. 7, 158 (2016).