An internal standard for the quantification of thymine
Related Products
Alternative(s)
36329Thymine-d4
Unlabeled Version(s)
38749Thymine
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Thymine-13C5,15N2

Item No. 41172

Technical Information
Formal Name
5-(methyl-13C)-2,4(1H,3H)-pyrimidinedione-2,4,5,6-13C4-1,3-15N2
CAS Number
2483830-13-1
Synonyms
  • 5-Methyluracil-13C5,15N2
Molecular Formula
[13C]5H6[15N]2O2
Formula Weight
Purity
≥98%
A solid
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Sparingly Soluble: 1-10 mg/ml
SMILES
O=[13C]([15NH][13CH]=[13C]1[13CH3])[15NH][13C]1=O
InChi Code
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)/i1+1,2+1,3+1,4+1,5+1,6+1,7+1
InChi Key
RWQNBRDOKXIBIV-BNUYUSEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Thymine-13C5,15N2 is intended for use as an internal standard for the quantification of thymine (Item No. 38749) by GC- or LC-MS. Thymine is a pyrimidine base.1 It forms complementary base pairs with the purine adenine (Item No. 18148) in DNA.1 Thymine is produced by the catabolism of thymidine (Item No. 20519) via thymidine phosphorylase.2 It is replaced with uracil (Item No. 26088) in RNA.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ghannam, J.Y., Wang, J., and Jan, A. Biochemistry, DNA Structure. 1-5 (2021).

    2. Brown, N.S., and Bicknell, R. Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis. Biochem. J. 334(Pt 1), 1-8 (1998).

    3. Banoub, J.H., Newton, R.P., Esmans, E., et alRecent developments in mass spectrometry for the characterization of nucleosides, nucleotides, oligonucleotides, and nucleic acids. Chem. Rev. 105(5), 1869-1915 (2005).