A peptide fragment of GLP-1
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GLP-1 (7-15) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Item No. 41256

Technical Information
Formal Name
L-histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartic acid, trifluoroacetate salt
Synonyms
  • Glucagon-like Peptide 1 (7-15)
Molecular Formula
C40H57N11O17 • XCF3COOH
Formula Weight
Purity
≥98%
A solid
Peptide Sequence
HAEGTFTSD-OH
DMSO: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CO)=O)[C@@H](C)O)=O)[C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O.FC(F)(F)C(O)=O
InChi Code
InChI=1S/C40H57N11O17.C2HF3O2/c1-18(45-34(61)23(41)12-22-14-42-17-44-22)33(60)46-24(9-10-29(56)57)35(62)43-15-28(55)50-31(19(2)53)38(65)47-25(11-21-7-5-4-6-8-21)36(63)51-32(20(3)54)39(66)49-27(16-52)37(64)48-26(40(67)68)13-30(58)59;3-2(4,5)1(6)7/h4-8,14,17-20,23-27,31-32,52-54H,9-13,15-16,41H2,1-3H3,(H,42,44)(H,43,62)(H,45,61)(H,46,60)(H,47,65)(H,48,64)(H,49,66)(H,50,55)(H,51,63)(H,56,57)(H,58,59)(H,67,68);(H,6,7)/t18-,19+,20+,23-,24-,25-,26-,27-,31-,32-;/m0./s1
InChi Key
APQCJFZPMJUJKN-JFNRVPBQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Glucagon-like peptide 1 (GLP-1) (7-15) is a peptide fragment of the endogenous incretin hormone GLP-1 (Item No. 24460).1 GLP-1 (7-15) is formed by cleavage of the peptide bond between Asp15 and Val16 in GLP-1 by neprilysin.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Manandhar, B., and Ahn, J.-M. Glucagon-like peptide-1 (GLP-1) analogs: Recent advances, new possibilities, and therapeutic implications. J. Med. Chem. 58(3), 1020-1037 (2015).