An EBI2 antagonist
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ML-401

Item No. 41450

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2E)-3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-2-propen-1-one
CAS Number
1597489-14-9
Molecular Formula
C20H20BrClN2O
Formula Weight
419.7
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlDMSO: Slightly soluble: 0.1-1 mg/ml
SMILES
BrC(C=C1)=CC=C1/C=C/C(N2CCN(CC2)CC3=CC=C(C=C3)Cl)=O
InChi Code
InChI=1S/C20H20BrClN2O/c21-18-6-1-16(2-7-18)5-10-20(25)24-13-11-23(12-14-24)15-17-3-8-19(22)9-4-17/h1-10H,11-15H2/b10-5+
InChi Key
NXTNVQJKGHAGAX-BJMVGYQFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $83

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    10 mg

    $158

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    25 mg

    $330

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    50 mg

    $620

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    Product Description

    ML-401 is an Epstein-Barr virus-induced G protein-coupled receptor 2 (EBI2) antagonist (IC50 = 1.03 nM).1 It inhibits RS11846 cell chemotaxis (IC50 = 4.533 nM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ardecky, R., Sergienko, E., Zou, J., et al. Functional antagonists of EBI-2. (2014).