An internal standard for the quantification of fenoprofen
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Unlabeled Version(s)
23835Fenoprofen (calcium salt hydrate)
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Fenoprofen-13C6 (sodium salt hydrate)

Item No. 41683

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-methyl-3-(phenoxy-1,2,3,4,5,6-13C6)-benzeneacetic acid, monosodium salt, hydrate
CAS Number
2687960-29-6
Molecular Formula
C9[13C]6H13O3 • Na [XH2O]
Formula Weight
270.2
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
CC(C1=CC=CC(O[13C]2=[13CH][13CH]=[13CH][13CH]=[13CH]2)=C1)C([O-])=O.[Na+].O
InChi Code
InChI=1S/C15H14O3.Na.H2O/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;;/h2-11H,1H3,(H,16,17);;1H2/q;+1;/p-1/i2+1,3+1,4+1,7+1,8+1,13+1;;
InChi Key
MUQAHZSOOWLDJC-UWTURDRMSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $582

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    Product Description

    Fenoprofen-13C6 is intended for use as an internal standard for the quantification of fenoprofen (Item No. 23835) by GC- or LC-MS. Fenoprofen is a non-steroidal anti-inflammatory drug (NSAID).1 It inhibits spontaneous and estradiol-stimulated prostaglandin F2α (PGF2α; Item Nos. 16010 | 16020) release by 84% in isolated rat uterine horns when used at a concentration of 33 μM. Fenoprofen (10 mg/kg, i.p.) reduces serum PGF2α levels in rats. It reduces acetic acid-induced writhing and stretching and formalin-induced licking behaviors in mice, however, it also induces the formation of gastric lesions in mice.2 Formulations containing fenoprofen have been used in the treatment of pain and the signs and symptoms of rheumatoid arthritis and osteoarthritis.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Patrono, C., Ciabattoni, G., and Grossi-Belloni, D. In vitro and in vivo inhibition of prostaglandin synthesis by fenoprofen, a non steroid anti-inflammatory drug. Pharmacol. Res. Commun. 6(5), 509-518 (1974).

    2. Agotegaray, M., Gumilar, F., Boeris, M., et al. Enhanced analgesic properties and reduced ulcerogenic effect of a mononuclear copper(II) complex with fenoprofen in comparison to the parent drug: Promising insights in the treatment of chronic inflammatory diseases. Biomed. Res. Int. 505987 (2014).