A peptide-lipid conjugate
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DSPE-PEG(2000)-Cyclo(RGDyK)

Item No. 41941

Technical Information
Synonyms
  • 1,2-Distearoyl Phosphatidylethanolamine-PEG(2000)-cRGD Peptide
  • 1,2-DSPE-PEG(2000)-cRGDyK
  • DSPE-PEG(2000)-RGD
  • Integrin-Targeting Peptide Conjugate
  • PE(18:0/18:0)-PEG(2000)-CycloRGDyK
Molecular Formula
(C2H4O)nC75H128N13O18P
MW
3,813.8 (Average)
200 µg of DSPE-PEG(2000)-cycloRGD conjugate
Applications
For dilution in ethanol and LNP formulations
SMILES
O=C(NCCOP(OCC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(O)=O)OCCN1C=C(CCCC(NCCCCC(NC([C@H](CC2=CC=C(O)C=C2)N3)=O)C(N[C@H](CCCNC(N)=N)C(NCC(N[C@H](CC(O)=O)C3=O)=O)=O)=O)=O)N=N1
InChi Code
InChI=1S/C77H132N13O19P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-41-70(96)106-57-62(109-71(97)42-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)58-108-110(103,104)107-51-49-82-77(102)105-52-50-90-56-60(88-89-90)37-35-40-67(92)80-47-34-33-38-64-73(99)85-63(39-36-48-81-76(78)79)72(98)83-55-68(93)84-66(54-69(94)95)75(101)87-65(74(100)86-64)53-59-43-45-61(91)46-44-59/h43-46,56,62-66,91H,3-42,47-55,57-58H2,1-2H3,(H,80,92)(H,82,102)(H,83,98)(H,84,93)(H,85,99)(H,86,100)(H,87,101)(H,94,95)(H,103,104)(H4,78,79,81)/t62?,63-,64?,65+,66-/m1/s1
InChi Key
QEVPGDHJMRPVFH-CPQWXSPQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    DSPE-PEG(2000)-Cyclo(RGDyK) is a peptide-lipid conjugate. It was prepared from DSPE-PEG(2000)-azide (Item No. 40710) and alkyne-cyclo(RGDyK) (Item No. 41722), a clickable form of the peptide αVβ3 integrin ligand cyclo(RGDyK) (Item No. 35173), via copper click chemistry. DSPE-PEG(2000)-Cyclo(RGDyK) is intended for use in the targeted delivery of lipid nanoparticles (LNPs) in vitro and in vivo.

    WARNING This product is not for human or veterinary use.