A protected L-tyrosine derivative
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Fmoc-Tyr(PO3H2)-OH

Item No. 41973

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-phosphono-L-tyrosine
CAS Number
147762-53-6
Synonyms
  • Fmoc-pTyr-OH
Molecular Formula
C24H22NO8P
Formula Weight
483.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
OC([C@H](CC1=CC=C(C=C1)OP(O)(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O
InChi Code
InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m0/s1
InChi Key
AMXUJIHSMANWDW-QFIPXVFZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Product Description

    Fmoc-Tyr(PO3H2)-OH is a protected derivative of L-tyrosine (Item No. 36333).1,2 It has been used in the synthesis of peptides and antibacterial-peptide conjugates.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ottinger, E.A., Xu, Q., and Barany, G. Intramolecular pyrophosphate formation during N alpha-9-fluorenylmethyloxycarbonyl (Fmoc) solid-phase synthesis of peptides containing adjacent phosphotyrosine residues. Pept. Res. 9(5), 223-228 (1996).

    2. Zhan, W., Gao, G., Liu, Z., et al. Enzymatic self-assembly of adamantane-peptide conjugate for combating Staphylococcus aureus infection. Adv. Healthc. Mater. 12(18), e2203283 (2023).