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Soyasaponin Ba is a saponin that has been found in P. vulgaris and has enzyme inhibitory and immune stimulatory activities.1,2 It is an inhibitor of aldose reductase 1 (Ki = 66 µM for the recombinant human enzyme).1 Soyasaponin Ba (50 µg/mouse) potentiates ovalbumin-induced increases in IgG and IgG1 serum levels in mice.2
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1. Soyasaponins from Zolfino bean as aldose reductase differential inhibitors. J. Enzyme Inhib. Med. Chem. 34(1), 350-360 (2019).
2. Haemolytic activity and adjuvant effect of soyasaponins and some of their derivatives on the immune responses to ovalbumin in mice. Int. Immunopharmacol. 18(2), 333-339 (2014).