A saponin with enzyme inhibitory and immune stimulatory activities
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Soyasaponin Ba

Item No. 42534

Technical Information
Formal Name
(3β,4β,22β)-22,23-dihydroxyolean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranosiduronic acid
CAS Number
114590-20-4
Synonyms
  • Soyasaponin M2
  • Soyasaponin V
Molecular Formula
C48H78O19
Formula Weight
Purity
≥98%
Formulation
A solid
DMSO: Soluble: ≥10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
[H][C@@]12CC(C)(C)C[C@@H](O)[C@]1(C)CC[C@]3(C)C2=CC[C@@]4([C@@]5(C)CC[C@H](O[C@@H]6O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)[C@](C)(CO)[C@](CC[C@@]34C)5[H])[H]
InChi Code
InChI=1S/C48H78O19/c1-43(2)16-22-21-8-9-26-45(4)12-11-28(46(5,20-51)25(45)10-13-48(26,7)47(21,6)15-14-44(22,3)27(52)17-43)64-42-38(34(58)33(57)36(65-42)39(60)61)67-41-37(32(56)30(54)24(19-50)63-41)66-40-35(59)31(55)29(53)23(18-49)62-40/h8,22-38,40-42,49-59H,9-20H2,1-7H3,(H,60,61)/t22-,23+,24+,25+,26+,27+,28-,29+,30-,31-,32-,33-,34-,35+,36-,37+,38+,40-,41-,42+,44+,45-,46+,47+,48+/m0/s1
InChi Key
WFRQIKSNAYYUJZ-BKQVBUAGSA-N
Origin
Plant/Glycine max
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Soyasaponin Ba is a saponin that has been found in P. vulgaris and has enzyme inhibitory and immune stimulatory activities.1,2 It is an inhibitor of aldose reductase 1 (Ki = 66 µM for the recombinant human enzyme).1 Soyasaponin Ba (50 µg/mouse) potentiates ovalbumin-induced increases in IgG and IgG1 serum levels in mice.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balestri, F., De Leo, M., Sorce, C., et alSoyasaponins from Zolfino bean as aldose reductase differential inhibitors. J. Enzyme Inhib. Med. Chem. 34(1), 350-360 (2019).

    2. Qiao, N., Liu, Q., Meng, H., et alHaemolytic activity and adjuvant effect of soyasaponins and some of their derivatives on the immune responses to ovalbumin in mice. Int. Immunopharmacol. 18(2), 333-339 (2014).