A quinoline fungicide
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Quinoxyfen

Item No. 42938

Technical Information
Formal Name
5,7-dichloro-4-(4-fluorophenoxy)-quinoline
CAS Number
124495-18-7
Synonyms
  • DE-795
Molecular Formula
C15H8Cl2FNO
Formula Weight
Purity
≥98%
Formulation
A solid
DMSO: Soluble: ≥ 10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
ClC1=CC(Cl)=CC2=NC=CC(OC3=CC=C(F)C=C3)=C21
InChi Code
InChI=1S/C15H8Cl2FNO/c16-9-7-12(17)15-13(8-9)19-6-5-14(15)20-11-3-1-10(18)2-4-11/h1-8H
InChi Key
WRPIRSINYZBGPK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Quinoxyfen is a quinoline fungicide.1 It reduces the incidence of grape powdery mildew and the mean proportion of infected berries when applied at a concentration of 292 ml/ha to grape vines at the end of bloom stage.2 Quinoxyfen reduces the feeding rate of G. fossarum (EC50 = 23.8 µg/L).1 It also reduces androgen-mediated transcriptional activity in a reporter assay using MDA-kb2 cells (IC20 = 4.79 µM) and is cytotoxic to MDA-kb2 cells (EC20 = 10.1 µM).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zubrod, J.P., Baudy, P., Schulz, R., et alEffects of current-use fungicides and their mixtures on the feeding and survival of the key shredder Gammarus fossarum. 150, 133-143 (2014).

    2. Warneke, B., Thiessen, L.D., and Mahaffee, W.F. Effect of fungicide mobility and application timing on the management of grape powdery mildew. Plant Dis. 104(4), 1167-1174 (2020).

    3. Orton, F., Rosivatz, E., Scholze, M., et alWidely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ. Health Perspect. 119(6), 794-800 (2011).