A dual NK1 and NK3 receptor antagonist
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Elinzanetant

Item No. 43016

Technical Information
Formal Name
N-[4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)-benzeneacetamide
CAS Number
929046-33-3
Synonyms
  • BAY-3427080
  • GSK1144814
  • NT-814
Molecular Formula
C33H35F7N4O3
Formula Weight
Purity
≥98%
Formulation
A solid
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
OC[C@H](CN1[C@@](COCC1)([H])C2)N2C3=NC=C(N(C(C(C)(C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)C)C(C5=C(C)C=C(F)C=C5)=C3
InChi Code
InChI=1S/C33H35F7N4O3/c1-19-9-23(34)5-6-26(19)27-13-29(44-16-25-18-47-8-7-43(25)15-24(44)17-45)41-14-28(27)42(4)30(46)31(2,3)20-10-21(32(35,36)37)12-22(11-20)33(38,39)40/h5-6,9-14,24-25,45H,7-8,15-18H2,1-4H3/t24-,25-/m0/s1
InChi Key
DWRIJNIPBUFCQS-DQEYMECFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Elinzanetant is a dual neurokinin-1 (NK1) and NK3 receptor antagonist.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hager, M., Goldstein, T., Fitz, V., et alElinzanetant, a new combined neurokinin-1/-3 receptor antagonist for the treatment of postmenopausal vasomotor symptoms. Expert Opin. Pharmacother. 25(7), 783-789 (2024).