A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
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α-hydroxy Triazolam-13C2-d4 (CRM)

A 100 µg/ml solution in methanol

Item No. 43154

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(8-chloro-6-(2-chlorophenyl-3,4,5,6-d4)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-1-yl-3a,4-13C2)methanol
Molecular Formula
C15[13C]2H8Cl2D4N4O
Formula Weight
365.2
Formulation (Request formulation change)
A 100 µg/ml solution in methanol
SMILES
OCC1=NN=[13C](N1C2=CC=C(Cl)C=C23)[13CH2]N=C3C4=C(Cl)C([2H])=C([2H])C([2H])=C4[2H]
InChi Code
InChI=1S/C17H12Cl2N4O/c18-10-5-6-14-12(7-10)17(11-3-1-2-4-13(11)19)20-8-15-21-22-16(9-24)23(14)15/h1-7,24H,8-9H2/i1D,2D,3D,4D,8+1,15+1
InChi Key
BHUYWUDMVCLHND-HYGSHXCFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 µg

    $44

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    Product Description

    α-hydroxy Triazolam-13C2-d4 (CRM) (Item No. 43154) is intended for use as an internal standard for the quantification of α-hydroxy triazolam (Item Nos. 40187 | 39390) by GC- or LC-MS. α-hydroxy Triazolam is categorized as a benzodiazepine. It is an active metabolite of triazolam (Item Nos. 39683 | 22577).1,2 It has anticonvulsant and sedative effects in mice.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Perloff, M.D., von Moltke, L.L., Court, M.H., et al. Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms. J. Pharmacol. Exp. Ther. 292(2), 618-628 (2000).

    2. Hester, J.B., Jr., and Von Voigtlander, P. 6-Aryl-4H-s-triazolo[4,3-α][1,4]benzodiazepines. Influence of 1-substitution on pharmacological activity. J. Med. Chem. 22(11), 1390-1398 (1979).