An anticholinergic agent
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Tropatepine

Item No. 43415

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-dibenzo[b,e]thiepin-11(6H)-ylidene-8-methyl-8-azabicyclo[3.2.1]octane
CAS Number
27574-24-9
Molecular Formula
C22H23NS
Formula Weight
333.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleMethanol: Soluble
SMILES
CN(C(CC1)C/2)C1CC2=C3C4=C(C=CC=C4)SCC5=C\3C=CC=C5
InChi Code
InChI=1S/C22H23NS/c1-23-17-10-11-18(23)13-16(12-17)22-19-7-3-2-6-15(19)14-24-21-9-5-4-8-20(21)22/h2-9,17-18H,10-14H2,1H3
InChi Key
JOQKFRLFXDPXHX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $83

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    5 mg

    $392

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    Product Description

    Tropatepine is an anticholinergic agent.1,2 It protects against sinistrotorsion syndrome induced by oxotremorine (Item No. 35707) in guinea pigs (ED50 = 0.2-0.5 mg/kg).1 Formulations containing tropatepine have been used in the treatment of neuroleptic-induced parkinsonian symptoms.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Boissier, J.R., and Ratouis, R. New tropane derivatives and their salts. (1970).

    2. Nigam, M., Leu-Semenescu, S., and Arnulf, I. Successful treatment of drug-resistant cataplexy with the anticholinergic drug tropatepine. J. Clin. Sleep Med. 17(4), 849-851 (2021).