A polarity-sensitive fluorescent probe for lipid rafts
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C-Laurdan

Item No. 43531

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-methyl-N-[6-(1-oxododecyl)-2-naphthalenyl]-glycine
CAS Number
959839-06-6
Molecular Formula
C25H35NO3
Formula Weight
397.6
Purity
≥98%
Emission
522 nm in water
Excitation
820 nm in water
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
CN(CC(O)=O)C1=CC=C2C(C=CC(C(CCCCCCCCCCC)=O)=C2)=C1
InChi Code
InChI=1S/C25H35NO3/c1-3-4-5-6-7-8-9-10-11-12-24(27)22-14-13-21-18-23(16-15-20(21)17-22)26(2)19-25(28)29/h13-18H,3-12,19H2,1-2H3,(H,28,29)
InChi Key
INSWREUMXDGFSD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $128

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    5 mg

    $608

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    Product Description

    C-Laurdan is a polarity-sensitive fluorescent probe for lipid rafts and a derivative of the fluorescent membrane probe laurdan (Item No. 19706).1 It displays a two-photon excitation maximum of 820 nm and one-photon absorption/emission maxima of 384/522 nm, respectively, in water. C-Laurdan fluorescence exhibits polarity-dependent spectral shifts, with emission at longer wavelengths in polar environments and shorter wavelengths in non-polar environments. It has been used in the study of lipid rafts and membrane lateral organization.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, H.M., Choo, H.-J., Jung, S.-Y., et al. A two-photon fluorescent probe for lipid raft imaging: C-laurdan. Chembiochem 8(5), 553-559 (2007).

    2. Dodes Traian, M.M., Flecha, F.L.G., and Levi, V. Imaging lipid lateral organization in membranes with C-laurdan in a confocal microscope. J. Lipid Res. 53(3), 609-616 (2012).