A 5-HT6 receptor antagonist
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SGS 518

Item No. 43670

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,6-difluoro-benzenesulfonic acid, 1-methyl-3-(1-methyl-4-piperidinyl)-1H-indol-5-yl ester
CAS Number
445441-26-9
Synonyms
  • LY483518
Molecular Formula
C21H22F2N2O3S
Formula Weight
420.5
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
FC1=C(S(OC2=CC3=C(C=C2)N(C=C3C4CCN(CC4)C)C)(=O)=O)C(F)=CC=C1
InChi Code
InChI=1S/C21H22F2N2O3S/c1-24-10-8-14(9-11-24)17-13-25(2)20-7-6-15(12-16(17)20)28-29(26,27)21-18(22)4-3-5-19(21)23/h3-7,12-14H,8-11H2,1-2H3
InChi Key
LYHNZWIPSZUYDT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $43

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    5 mg

    $194

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    10 mg

    $280

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    25 mg

    $537

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    Product Description

    SGS 518 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT6.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Upton, N., Chuang, T.T., Hunter, A.J., et al. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer’s disease. Neurotherapeutics 5(3), 458-469 (2008).