A multi-kinase inhibitor
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SB-633825

Item No. 43706

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[5-(6-methoxy-2-naphthalenyl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]-pyridine
CAS Number
956613-01-7
Molecular Formula
C28H25N3O3S
Formula Weight
483.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
SMILES
O=S(C1=CC=C(C2=NC(C3=CC=NC=C3)=C(N2C)C4=CC5=C(C=C(C=C5)OC)C=C4)C(C)=C1)(C)=O
InChi Code
InChI=1S/C28H25N3O3S/c1-18-15-24(35(4,32)33)9-10-25(18)28-30-26(19-11-13-29-14-12-19)27(31(28)2)22-6-5-21-17-23(34-3)8-7-20(21)16-22/h5-17H,1-4H3
InChi Key
ZDSNJSQTPLXCSG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    25 mg

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    Product Description

    SB-633825 is a multi-kinase inhibitor.1 It inhibits tunica interna endothelial kinase 2 (Tie2), serine/threonine kinase 10 (STK10), and breast tumor kinase (BRK; IC50s = 3.5, 66, and 150 nM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Elkins, J.M., Fedele, V., Szklarz, M., et al. Comprehensive characterization of the published kinase inhibitor set. Nat. Biotechnol. 34(1), 95-103 (2016).