An anticoccidial agent
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Labeled Version(s)
43810Robenidine-d8 (hydrochloride)
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Robenidine (hydrochloride)

Item No. 43792

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2′-bis[(4-chlorophenyl)methylene]-carbonimidic dihydrazide, monohydrochloride
CAS Number
25875-50-7
Molecular Formula
C15H13Cl2N5 • HCl
Formula Weight
370.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
ClC1=CC=C(C=C1)C=NNC(NN=CC2=CC=C(C=C2)Cl)=N.Cl
InChi Code
InChI=1S/C15H13Cl2N5.ClH/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12;/h1-10H,(H3,18,21,22);1H
InChi Key
LTWIBTYLSRDGHP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    50 mg

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    Cayman Chemical
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    Product Description

    Robenidine is an anticoccidial agent.1 It is also active against methicillin-resistant S. aureus (MRSA) and vancomycin-resistant enterococci (VRE; MICs = 6.1 and 7.4 µM, respectively).2 Dietary administration of robenidine reduces weight gain, decreases intestinal lesion and oocyst numbers, and increases survival in E. acervulina-, E. brunetti-, E. mivati-, E. necatrix-, or E. tenella-infected chickens. Formulations containing robenidine have been used in animal feed for the prevention of coccidiosis or control of necrotic enteritis in chickens.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kennett, R.L., Kantor, S., and Gallo, A. Efficacy studies with robenidine, a new type of anticoccidial, in the diet. Poult. Sci. 53(3), 978-986 (1974).

    2. Abraham, R.J., Stevens, A.J., Young, K.A., et al. Robenidine analogues as gram-positive antibacterial agents. J. Med. Chem. 59(5), 2126-2138 (2016).