A screening set of cholesterols, cholesterol analogs, and bile acids for use in LNP formulations
Features
  • Contains 13 compounds
  • Includes a variety of cholesterols, cholesterol analogs, and bile acids
  • Use the "Bulk & Custom" form to add/remove compounds or to request bar-coded vials
  • Use with LipidLaunch™ Helper Lipid Set (Item No. 42831)
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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LipidLaunch™ Cholesterol Analog LNP Screening Set

Item No. 43889

Product Insert (PDF)
Technical Information
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Cayman Chemical
    Product Description

    The LipidLaunch™ Cholesterol Analog LNP Screening Set includes two types of cholesterol, five cholesterol analogs, and six bile acids to screen for use in lipid nanoparticle (LNP) formulations. Each lipid in the set is supplied in a vial containing 10 mg of lipid for ease of addition to lipid mixes for LNP formulation. Lipids selected for this screening set are some of the most cited cholesterol analogs and bile acids used in nucleic acid-cargo LNPs. LNPs containing these lipids in combination with a cationic and/or ionizable cationic lipid, phospholipid, and PEGylated lipid have been used to encapsulate mRNA, plasmid DNA, siRNA, and other nucleic acid cargo for intracellular delivery. For more information, please see Cayman's LNP guide: Lipid Nanoparticle Formulation: Basic Concepts & Preparation Procedures.

    WARNING This product is not for human or veterinary use.