An anesthetic
Related Products
Isomer(s)
23989Isoflurane
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Enflurane

Item No. 44218

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane
CAS Number
13838-16-9
Synonyms
  • NSC 115944
Molecular Formula
C3H2ClF5O
Formula Weight
184.5
Purity
≥98%
Formulation (Request formulation change)
A liquid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
FC(OC(F)(C(Cl)F)F)F
InChi Code
InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H
InChi Key
JPGQOUSTVILISH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    100 mg

    $45

    Add

    250 mg

    $107

    Add

    500 mg

    $203

    Add

    1 g

    $338

    Add
    Product Description

    Enflurane is an anesthetic.1 It selectively binds to voltage-gated sodium (Nav) channels and GABAA receptors over L-type calcium (Cav1) channels (IC50s = 0.539, 0.946, and >3 mM, respectively). Enflurane protects against ischemia-induced decreases in left ventricular developed pressure in Langendorff isolated perfused rat hearts.2 It decreases mean systolic blood pressure and induces muscle twitching in dogs.3 Enflurane has proconvulsant activity in dogs during hypocapnia.4 Formulations containing enflurane have previously been used as general anesthetics and analgesics during labor and delivery.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lingamaneni, R., and Hemmings, H.C., Jr. Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABAA receptors. Br. J. Anaesth. 90(2), 199-211 (2003).

    2. Schlack, W., Preckel, B., Stunneck, D., et al. Effects of halothane, enflurane, isoflurane, sevoflurane and desflurane on myocardial reperfusion injury in the isolated rat heart. Br. J. Anaesth. 81(6), 913-919 (1998).

    3. Klide, A.M. Cardiopulmonary effects of enflurane and isoflurane in the dog. Am. J. Vet. Res. 37(2), 127-131 (1976).

    4. Scheller, M.S., Nakakimura, K., Fleischer, J.E., et al. Cerebral effects of sevoflurane in the dog: Comparison with isoflurane and enflurane. Br. J. Anaesth. 65(3), 388-392 (1990).