An ω-7 fatty acid
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trans-Vaccenic Acid (sodium salt)

Item No. 44257

Product Insert (PDF)
Technical Information
Formal Name
(11E)-11-octadecenoic acid, monosodium salt
CAS Number
104233-68-3
Synonyms
  • C18:1(11E)
  • C18:1 n-7
  • FA 18:1
  • trans-11-Octadecenoic Acid
Molecular Formula
C18H33O2 • Na
Formula Weight
Purity
≥98%
A solid
Methanol: Sparingly soluble: 1-10 mg/ml
SMILES
[O-]C(CCCCCCCCC/C=C/CCCCCC)=O.[Na+]
InChi Code
InChI=1S/C18H34O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h7-8H,2-6,9-17H2,1H3,(H,19,20);/q;+1/p-1/b8-7+;
InChi Key
NKZQDAISLCDHHU-USRGLUTNSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    trans-Vaccenic acid is an ω-7 fatty acid that has been found in bovine milk fats.1 Dietary administration of trans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome.2 It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Santora, J.E., Palmquist, D.L., and Roehrig, K.L. Trans-vaccenic acid is desaturated to conjugated linoleic acid in mice. J. Nutr. 130(2), 208-215 (2000).

    2. Jacome-Sosa, M.M., Borthwick, F., Mangat, R., et alDiets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome. J. Nutr. Biochem. 25(7), 692-701 (2014).

    3. Bassett, C.M., Edel, A.L., Patenaude, A.F., et alDietary vaccenic acid has antiatherogenic effects in LDLr-/- mice. J. Nutr. 140(1), 18-24 (2010).