An azo dye
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Allura Red AC

Item No. 44514

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-hydroxy-5-[2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-2-naphthalenesulfonic acid, disodium salt
CAS Number
25956-17-6
Synonyms
  • C.I. 16035
  • E129
  • FD&C Red No. 40
  • Food Red No. 40
  • Red 40
Molecular Formula
C18H14N2O8S2 • 2Na
Formula Weight
496.4
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
CC1=CC(N=NC2=C(C=CC3=CC(S([O-])(=O)=O)=CC=C23)O)=C(C=C1S([O-])(=O)=O)OC.[Na+].[Na+]
InChi Code
InChI=1S/C18H16N2O8S2.2Na/c1-10-7-14(16(28-2)9-17(10)30(25,26)27)19-20-18-13-5-4-12(29(22,23)24)8-11(13)3-6-15(18)21;;/h3-9,21H,1-2H3,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2
InChi Key
CEZCCHQBSQPRMU-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Allura Red AC is an azo dye.1 It displays an absorbance maximum at 504 nm.1,2 Allura Red AC (70 mg/kg) decreases novel object exploration time in the novel objection recognition test and reduces medial prefrontal cortex volume, neuron and glial cell numbers, and dendrite length in rats.3 Oral administration of Allura Red AC (14 mg/kg) induces DNA damage in colon epithelial cells in mice.4 It also decreases survival and increases intestinal inflammation when administered in combination with a high-fat diet in mice. Allura Red AC has been found in wastewater.2 Formulations containing Allura Red AC have been used as food dyes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    2. Şen, N.E., and Şenol, Z.M. Effective removal of Allura red food dye from water using cross-linked chitosan-diatomite composite beads. Int. J. Biol. Macromol. 253(Pt. 1), 126632 (2023).

    3. Noorafshan, A., Hashemi, M., Karbalay-Doust, S., et al. High dose Allura Red, rather than the ADI dose, induces structural and behavioral changes in the medial prefrontal cortex of rats and taurine can protect it. Acta Histochem. 120(6), 586-594 (2018).

    4. Zhang, Q., Chumanevich, A.A., Nguyen, I., et al. The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice. Toxicol. Rep. 11, 221-232 (2023).