An anthraquinone textile dye
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Acid Blue 25

Item No. 44528

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-amino-9,10-dihydro-9,10-dioxo-4-(phenylamino)-2-anthracenesulfonic acid, monosodium salt
CAS Number
6408-78-2
Synonyms
  • AB25
  • 2-Anthraquinonesulfonic Acid
  • C.I. 62055
  • C.I. Acid Blue 25
Molecular Formula
C20H13N2O5S • Na
Formula Weight
416.4
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
λmax
254, 630 nm
SMILES
O=C1C2=C(C(C3=C(NC4=CC=CC=C4)C=C(S(=O)([O-])=O)C(N)=C13)=O)C=CC=C2.[Na+]
InChi Code
InChI=1S/C20H14N2O5S.Na/c21-18-15(28(25,26)27)10-14(22-11-6-2-1-3-7-11)16-17(18)20(24)13-9-5-4-8-12(13)19(16)23;/h1-10,22H,21H2,(H,25,26,27);/q;+1/p-1
InChi Key
LIKZXCROQGHXTI-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Acid blue 25 is an anionic anthraquinone textile dye.1 It displays an absorption maximum at 600 nm. Acid blue 25 inhibits NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1; Ki = 22 nM).2 It also activates large-conductance calcium-activated potassium channels (KCa/BK) in rabbit bladder smooth muscle preparations in an inside/out patch-clamp assay (EC50 = 5.9 µM).3 Acid blue 25 has been found as a contaminant in wastewater.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bongard, R.D., Lepley, M., Gastonguay, A., et al. Heterogeneous photocatalytic degradation of the anthraquinonic dye, Acid Blue 25 (AB25): A kinetic approach. J. Photochem. Photobiol. A Chem. 168(1-2), 23-30 (2019).

    2. Prestera, T., Prochaska, H.J., and Talalay, P. Inhibition of NAD(P)H:(quinone-acceptor) oxidoreductase by cibacron blue and related anthraquinone dyes: A structure-activity study. Biochemistry 31(3), 824-833 (1992).

    3. Roy, S., Large, R.J., Akande, A.M., et al. Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels. Eur. J. Med. Chem. 75, 426-437 (2014).