A saturated acyl CoA and metabolite of 3-oxovalproyl-CoA
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Pentanoyl-Coenzyme A (lithium salt)

Item No. 44598

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-pentanoate, coenzyme A, lithium salt
CAS Number
108392-07-0
Synonyms
  • C5-CoA
  • Pentanoyl-Coenzyme A
  • Valeryl-CoA
  • Valeryl-Coenzyme A
Molecular Formula
C26H44N7O17P3S • XLi
Formula Weight
851.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile:Water (1:1): Sparingly Soluble: 1-10 mg/ml
SMILES
O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCC)=O)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Li]
InChi Code
InChI=1S/C26H44N7O17P3S.Li/c1-4-5-6-17(35)54-10-9-28-16(34)7-8-29-24(38)21(37)26(2,3)12-47-53(44,45)50-52(42,43)46-11-15-20(49-51(39,40)41)19(36)25(48-15)33-14-32-18-22(27)30-13-31-23(18)33;/h13-15,19-21,25,36-37H,4-12H2,1-3H3,(H,28,34)(H,29,38)(H,42,43)(H,44,45)(H2,27,30,31)(H2,39,40,41);/t15-,19-,20-,21+,25-;/m1./s1
InChi Key
OZIJYOFQOCLLGN-WADKRTIVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $49

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    1 mg

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    5 mg

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    Product Description

    Pentanoyl-CoA is a metabolite of 3-oxovalproyl-CoA and a derivative of coenzyme A (CoA; Item Nos. 16147 | 21499 | 21722) that contains the short-chain saturated fatty acid pentanoic acid.1 It is formed from 3-oxovalproyl-CoA by mitochondrial thiolases. Hepatic levels of pentanoyl-CoA and propionyl-CoA are increased in a model of spontaneous colorectal cancer using Apc+/Min-FCCC mice fed a low- or high-fat diet.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Silva, M.F., Ruiter, J.P., Overmars, H., et al. Complete β-oxidation of valproate: Cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase. Biochem. J. 362(Pt 3), 755-760 (2002).

    2. Dazard, J.-E., Sandlers, Y., Doerner, S.K., et al. Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancer. BMC Syst. Biol. 8:72, (2014).