BSA-Oleate Monounsaturated Fatty Acid Complex (10 mM)

BSA-Oleate Monounsaturated Fatty Acid Complex (10 mM) is composed of oleic acid (Item Nos. 90260 | 24659) and fatty acid-free bovine serum albumin (BSA) at an approximately 6:1 molar ratio of oleate:BSA. It can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring lipid metabolism and inflammatory signaling pathways.¹ It has been used in the study of lipid accumulation in hepatic steatosis.^2,3 Cayman’s BSA-Oleate Monounsaturated Fatty Acid Complex (10 mM) is suitable for use in short-term cell culture applications (acute treatment to 18 hours); however, for long-term applications (25+ hours) the product should be filter-sterilized using a 0.2 µm filter and sterile receptacle, which will not affect its performance. This product can be used to achieve higher concentrations or perform larger experiments than can be achieved with BSA-Oleate Monounsaturated Fatty Acid Complex (5 mM) (Item No. 29557). For best results, it is recommended that this product be used in conjunction with Cayman’s BSA Control for BSA-Fatty Acid Complexes (10 mM) (Item No. 44217), prepared with fatty acid-free BSA.

WARNING This product is not for human or veterinary use.

1. Alsabeeh, N., Chausse, B., Kakimoto, P.A., et al. Cell culture models of fatty acid overload: Problems and solutions. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1863(2), 143-151 (2018).

2. De Siervi, S., Mantovani, S., Oliviero, B., et al. Development, expansion, and histological characterization of patient-derived liver organoids for drug screening and disease modeling. Bio. Protoc. 16(5), e5631 (2026).

3. Bonanini, F., Dinkelberg, R., Torregrosa, M.C., et al. A microvascularized in vitro liver model for disease modeling and drug discovery. Biofabrication 17(1), (2024).