A BSA complex with oleic acid
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BSA-Oleate Monounsaturated Fatty Acid Complex (5 mM)

Item No. 29557

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Bovine Serum Albumin-OA
  • Bovine Serum Albumin-Oleate
  • BSA-OA
  • BSA-9(Z)-Octadecenoic Acid
Formulation (Request formulation change)
5 mM Oleate:0.8 mM BSA (6:1 oleate:BSA) in 150 mM sodium chloride, pH 7.4
Applications
Lipid droplet assays, Lipid-mediated cellular stress/MASLD/MASH assays, Metabolic flux/FAO assays
Origin
Animal/Bovine
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 ml

    $182

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    Product Description

    BSA-Oleate Monounsaturated Fatty Acid Complex (5 mM) is composed of oleic acid (Item Nos. 90260 | 24659) and fatty acid-free bovine serum albumin (BSA) at an approximately 6:1 molar ratio of oleate:BSA. It was prepared under sterile conditions, then filtered and aliquoted into sterile vials. Cayman's BSA-Oleate Monounsaturated Fatty Acid Complex (5 mM) can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring lipid metabolism and inflammatory signaling pathways.1 It has been used in the study of lipid accumulation in hepatic steatosis.2,3 Cayman’s BSA-Oleate Monounsaturated Fatty Acid Complex (5 mM) is suitable for use in short- and long-term cell culture applications (25+ hours). For best results, it is recommended that this product be used in conjunction with Cayman’s BSA Control for BSA-Fatty Acid Complexes (5 mM) (Item No. 29556), prepared with fatty acid-free BSA. A BSA-oleate complex is also available as part of Cayman’s BSA-Oleate Reagent Set (5 mM) (Item No. 44712).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Alsabeeh, N., Chausse, B., Kakimoto, P.A., et al. Cell culture models of fatty acid overload: Problems and solutions. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1863(2), 143-151 (2018).

    2. De Siervi, S., Mantovani, S., Oliviero, B., et al. Development, expansion, and histological characterization of patient-derived liver organoids for drug screening and disease modeling. Bio. Protoc. 16(5), e5631 (2026).

    3. Bonanini, F., Dinkelberg, R., Torregrosa, M.C., et al. A microvascularized in vitro liver model for disease modeling and drug discovery. Biofabrication 17(1), (2024).

    Product Citations

    Abraham, E., Kostina, A., Volmert, B., et al. A retinoic acid: YAP1 signaling axis controls atrial lineage commitment. Cell Rep. 44(5), 115687 (2025).

    Bonglack, E.N., Hill, K.K., Barry, A.P., et al. Fatty acid desaturases link cell metabolism pathways to promote proliferation of Epstein-Barr virus-infected B cells. PLoS Pathog. 21(5), e1012685 (2025).

    Peña de la Sancha, P., Wieser, B.I., Schauer, S., et al. Lipolysis-derived fatty acids are needed for homeostatic control of sterol element-binding protein-1c driven hepatic lipogenesis. Commun. Biol. 8(1), 588 (2025).

    Patil, N.Y., Rus, I., Ampadu, F., et al. Cinnabarinic acid protects against metabolic dysfunction-associated steatohepatitis by activating aryl hydrocarbon receptor-dependent AMPK signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 328(4), G433-G447 (2025).

    Soultsioti, M., de Jong, A.W.M., Blomberg, N., et al. Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles. J. Virol. 99(3), e0228224 (2025).

    Galigniana, N.M., Abdelhalim, M., Collas, P., et al. Transcriptional and metabolic changes following repeated fasting and refeeding of adipose stem cells highlight adipose tissue resilience. Nutrients 16(24), 4310 (2024).

    Das, D., Sharma, M., Gahlot, D., et al. VPS4A is the selective receptor for lipophagy in mice and humans. Mol. Cell. 84(22), 4436-4453.e4438 (2024).

    Murthy, D., Dutta, D., Attri, K.S., et al. CD24 negativity reprograms mitochondrial metabolism to PPARα and NF-κB-driven fatty acid β-oxidation in triple-negative breast cancer. Cancer Lett. 587, 216724 (2024).

    Wan, N., Hong, Z., Parson, M.A.H., et al. Spartin-mediated lipid transfer facilitates lipid droplet turnover. Proc. Nat. Acad. Sci. USA 121(3), e2314093121 (2024).

    Handlin, L.J., Macchi, N.L., Dumaire, N.L.A., et al. Membrane lipid nanodomains modulate HCN pacemaker channels in nociceptor DRG neurons. Nat. Commun. 15(1), 9898 (2024).

    Aleman, J., K, R., Wiegand, C., et al. A metabolic dysfunction-associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system. Commun. Biol. 7(1), 1317 (2024).

    Li, H., Li, D., Ledru, N., et al. Transcriptomic, epigenomic, and spatial metabolomic cell profiling redefines regional human kidney anatomy. Cell Metab. 36(5), 1105-1125 (2024).

    Li, X., Gamuyao, R., Wu, M.-L., et al. A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction. J. Cell Biol. 223(9), e202311126 (2024).

    Lin, D., Gold, A., Kaye, S., et al. Arachidonic acid mobilization and peroxidation promote microglial dysfunction in Aβ pathology. J. Neurosci. 44(31), e0202242024 (2024).

    Dall'Agnese, A., Platt, J.M., Zheng, M.M., et al. The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance. Nat. Commun. 13(1), 7522 (2022).

    Li, H., Dixon, E.E., Wu, H., et al. Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis. Cell Metab. 34(12), 1977-1998 (2022).

    Qi, G., Mi, Y., and Yin, F. Characterizing brain metabolic function ex vivo with acute mouse slice punches. STAR Protoc. 2(2), 100559 (2021).