A Certified Reference Material of tauroursodeoxycholic acid
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Tauroursodeoxycholic Acid (CRM)

Item No. 44871

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24yl]amino]-ethanesulfonic acid
CAS Number
14605-22-2
Synonyms
  • 3α,7β-dihydroxy-5β-cholanoyl Taurine
  • TUDCA
  • UR-906
Molecular Formula
C26H45NO6S
Formula Weight
A 1 mg/ml solution in methanol
SMILES
C[C@H](CCC(NCCS(O)(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1
InChi Key
BHTRKEVKTKCXOH-LBSADWJPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Tauroursodeoxycholic acid (CRM) (Item No. 44871) is a certified reference material categorized as a conjugated bile acid.1,2 It is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Item No. 15121). Serum levels of tauroursodeoxycholic acid are increased in individuals with intrahepatic cholestasis of pregnancy (ICP).3 This product is intended for use in analytical research applications. This product is also available as a general research tool (Item Nos. 20277 | 9003379).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Beuers, U. Effects of bile acids on hepatocellular signaling and secretion. Yale J. Biol. Med. 70(4), 341-346 (1997).

    2. Boatright, J.H., Nickerson, J.M., Moring, A.G., et alBile acids in treatment of ocular disease. J. Ocul. Biol. Dis. Infor. 2(3), 149-159 (2009).

    3. Yang, Z., Yao, M., Zhang, C., et alApplication of metabolomics in intrahepatic cholestasis of pregnancy: A systematic review. Eur. J. Med. Res. 27(1), 178 (2022).