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21871Propafenone (hydrochloride)
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Propafenone (hydrochloride)

Item No. 44945

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone, monohydrochloride
CAS Number
34183-22-7
Molecular Formula
C21H27NO3 • HCl
Formula Weight
377.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
O=C(C1=CC=CC=C1OCC(CNCCC)O)CCC2=CC=CC=C2.Cl
InChi Code
InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
InChi Key
XWIHRGFIPXWGEF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Propafenone (hydrochloride) (Item No. 44945) is an analytical reference standard categorized as a class IC antiarrhythmic agent.1 Propafenone has been associated with accidental and intentional overdose.1,2,3 Formulations containing propafenone have been used in the treatment of cardiac arrhythmias. This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 21871).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zeljković, I., Bulj, N., Kolačević, M., et al. Failure of intracardiac pacing after fatal propafenone overdose: A case report. J. Emerg. Med. 54(4), e65-e68 (2018).

    2. D'Orazio, L., and Curtis, J.A. Overdose of propafenone surreptitiously sold as "Percocet". J. Emerg. Med. 41(2), 172-175 (2011).

    3. Keramari, S., Poutoglidis, A., Poutoglidou, F., et al. Propafenone poisoning of a female adolescent after a suicide attempt. Cureus 13(7), e16576 (2021).