An aromatic amine antioxidant and rubber additive
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di-AMS

Item No. 45196

Technical Information
Formal Name
4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]-benzenamine
CAS Number
10081-67-1
Synonyms
  • Bis(4-(2-phenylpropan-2-yl)phenyl)amine; 4,4'-Bis(α,α-dimethylbenzyl)diphenylamine
  • DCDPA
  • 4,4′-Dicumyldiphenylamine
Molecular Formula
C30H31N
Formula Weight
Purity
≥98%
A solid
SMILES
CC(C1=CC=CC=C1)(C)C(C=C2)=CC=C2NC(C=C3)=CC=C3C(C)(C)C4=CC=CC=C4
InChi Code
InChI=1S/C30H31N/c1-29(2,23-11-7-5-8-12-23)25-15-19-27(20-16-25)31-28-21-17-26(18-22-28)30(3,4)24-13-9-6-10-14-24/h5-22,31H,1-4H3
InChi Key
UJAWGGOCYUPCPS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    di-AMS is a non-p-phenylenediamine (non-PPD) aromatic amine antioxidant and rubber additive.1,2 It increases progesterone levels in NCI H295R adrenocortical carcinoma cells when used at a concentration of 1.2 µM.3 It has been found in dust, handwipes, and urine.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guo, Z., Cheng, Z., Zhang, S., et al. Unexpected exposure risks to emerging aromatic amine antioxidants and p-phenylenediamine quinones to residents: Evidence from external and internal exposure as well as hepatotoxicity evaluation. Environ. Health Online ahead of print, (2024).

    2. Chen, X., Sun, S., Xu, P., et al. Rubber additives and relevant oxidation products in groundwater in a central China region: Levels, influencing factors and exposure. Environ. Pollut. 363(Pt. 1), 125155 (2024).

    3. Cardona, B., and Rudel, R.A. Application of an in vitro assay to identify chemicals that increase estradiol and progesterone synthesis and are potential breast cancer risk factors. Environ. Health Perspect. 129(7), 77003 (2021).