A rubber vulcanization accelerator
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TPG

Item No. 45200

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N′,N′′-triphenyl-guanidine
CAS Number
101-01-9
Synonyms
  • NSC 4051
  • 1,2,3-Triphenylguanidine
Molecular Formula
C19H17N3
Formula Weight
287.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
C1(/N=C(NC2=CC=CC=C2)/NC3=CC=CC=C3)=CC=CC=C1
InChi Code
InChI=1S/C19H17N3/c1-4-10-16(11-5-1)20-19(21-17-12-6-2-7-13-17)22-18-14-8-3-9-15-18/h1-15H,(H2,20,21,22)
InChi Key
FUPAJKKAHDLPAZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $33

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    10 g

    $63

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    25 g

    $149

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    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

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    Product Description

    TPG is a rubber vulcanization accelerator.1 TPG is associated with increased urinary levels of the oxidative stress biomarkers 8-hydroxyguanosine (8-OHG; Item No. 89300) and dityrosine (di-Y; Item No. 27657).2 TPG has been found in indoor dust and as a contaminant in soil.1,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, Z.-M., and Kannan, K. Occurrence of 1,3-diphenylguanidine, 1,3-di-o-tolylguanidine, and 1,2,3-triphenylguanidine in indoor dust from 11 countries: Implications for human exposure. Environ. Sci. Technol. 57(15), 6129-6138 (2023).

    2. Zhang, S., Zhou, Z., Wang, P., et al. Oxidative damage induced by daily exposure to primary and emerging aromatic amines: Insights from large scale biomonitoring and cell-based high-throughput PCR array analysis. J. Hazard. Mater. 496, 139300 (2025).

    3. Li, Z.M., Pal, V.K., Kannan, P., et al. 1,3-Diphenylguanidine, benzothiazole, benzotriazole, and their derivatives in soils collected from northeastern United States. Sci. Total Environ. 887, 164110 (2023).