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Chlorphine (hydrochloride)

Item No. 45280

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[1-[1-(4-chlorophenyl)ethyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, monohydrochloride
Molecular Formula
C20H22ClN3O • HCl
Formula Weight
392.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
CC(C1=CC=C(Cl)C=C1)N2CCC(N3C(NC4=C3C=CC=C4)=O)CC2.Cl
InChi Code
InChI=1S/C20H22ClN3O.ClH/c1-14(15-6-8-16(21)9-7-15)23-12-10-17(11-13-23)24-19-5-3-2-4-18(19)22-20(24)25;/h2-9,14,17H,10-13H2,1H3,(H,22,25);1H
InChi Key
WQGTVPZYOVCGEY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $87

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    5 mg

    $392

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    Cayman Chemical
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    Product Description

    Chlorphine (hydrochloride) (Item No. 45280) is an analytical reference standard categorized as an opioid.1 Chlorphine is a metabolite of N-propionitrile chlorphine (Item Nos. 45358 | 40326).2 Chlorphine induces respiratory depression in mice.1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vandeputte, M.M., Bilel, S., Tirri, M., et al. Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization. Neuropharmacology 260, 110113 (2024).

    2. Bassman, J.R., Layle, N.K., Goodwin, S.K., et al. Cayman novel psychoactive substances metabolism monograph. 4, 1-8 (2025).