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nor-Orphine

Item No. 37339

Product Insert (PDF)Technical Brief (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Orphine N-desalkyl metabolite
  • N-desalkyl Orphine
Technical Information
Formal Name
1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one
CAS Number
20662-53-7
Molecular Formula
C12H15N3O
Formula Weight
217.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
O=C1NC2=C(N1C3CCNCC3)C=CC=C2
InChi Code
InChI=1S/C12H15N3O/c16-12-14-10-3-1-2-4-11(10)15(12)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,16)
InChi Key
BYNBAMHAURJNTR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    nor-Orphine (Item No. 37339) is an analytical reference standard categorized as an opioid metabolite.1 nor-Orphine is a metabolite of brorphine (Item Nos. 34184 | 27816) and a potential metabolite of various other orphines based on the published metabolism of brorphine.1,2 It is also a precursor in the synthesis of various orphines. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Krotulski, A.J., Papsun, D.M., Noble, C., et al. Brorphine-investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography-mass spectrometry. J. Forensic Sci. 66(2), 664-676 (2021).

    2. Vandeputte, M.M., Bilel, S., Tirri, M., et al. Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization. Neuropharmacology 260, 110113 (2024).