A set containing 6-PPD-Q standards intended for LC-MS
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6-PPD-Q Standards Set

Item No. 45452

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • EPA Draft Method 1634 Standards Set
  • 6-PPD-quinone Standards Set
Formulation (Request formulation change)
A 100 µg/ml solution in acetonitrile
Shipping & Storage Information
Storage
2°C to 8°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 ea

    $395

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    Product Description

    6-PPD-Q Standards Set (Item No. 45452) is a set of standards containing 6-PPD-Q (CRM), 13C6-6-PPD-Q, and 6-PPD-Q-d5. 6-PPD-Q is a substituted p-phenylenediamine (PPD) quinone, oxidized transformation product of the tire rubber antioxidant 6-PPD (Item No. 38246), and an environmental toxicant.1 6-PPD-Q has been detected as a contaminant in atmospheric particles, road dust, and various aquatic sources, including surface water, stormwater, and wastewater, among other media.1,2 6-PPD-Q is highly toxic to aquatic organisms, including salmon and zebrafish, and induces oxidative stress, DNA damage, inflammation, and reproductive dysfunction in model organisms.1 The standards in this set are designed for use as reference standards for analytical testing of 6-PPD-Q in environmental samples by LC-MS using the EPA’s Draft Method 1634.3 Each standard is supplied as a ready-to-use 100 µg/ml solution in an amber ampule in which the headspace has been purged with argon.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, S., Tang, J., Qiu, Z., et al. Environmental and human health risks of 6PPD and 6PPDQ: Assessment and implications. Toxics 13(10), 873 (2025).

    2. Bohara, K., Timilsina, A., Adhikari, K., et al. A mini review on 6PPD quinone: A new threat to aquaculture and fisheries. Environ. Pollut. 340(Pt 2), 122828 (2024).

    3.  DRAFT method 1634. Determination of 6PPD-quinone in aqueous matrices using liquid chromatography with tandem mass spectrometry (LC/MS/MS). 2024, (2024).