An inverse agonist of CAR
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

S 07662

Item No. 45488

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(2-methyl-3-benzofuranyl)methyl]-N′-(2-thienylmethyl)-urea
CAS Number
883226-64-0
Molecular Formula
C16H16N2O2S
Formula Weight
300.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
CC1=C(CNC(NCC2=CC=CS2)=O)C3=C(O1)C=CC=C3
InChi Code
InChI=1S/C16H16N2O2S/c1-11-14(13-6-2-3-7-15(13)20-11)10-18-16(19)17-9-12-5-4-8-21-12/h2-8H,9-10H2,1H3,(H2,17,18,19)
InChi Key
UITFWLJMEZPXOF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $39

    Add

    5 mg

    $176

    Add

    10 mg

    $312

    Add
    Product Description

    S 07662 is an inverse agonist of the constitutive androstane receptor (CAR).1 It stabilizes the ligand-binding domain of human CAR, increases the recruitment of nuclear receptor co-repressor (NCOR), and reduces CAR activity (IC50 = 0.7 µM for the human receptor in a cell-based assay).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sengupta, N., Jović, M., Barnaeva, E., et al. A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha. J. Lipid Res. 60(3), 683-693 (2019).