An oxidized transformation product of 6-PPD
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6-PPD-Q (solution)

Item No. 45543

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(1,3-dimethylbutyl)amino]-5-(phenylamino)-2,5-cyclohexadiene-1,4-dione
CAS Number
2754428-18-5
Synonyms
  • 6-PPD-quinone
Molecular Formula
C18H22N2O2
Formula Weight
298.4
Purity
≥95%
Formulation (Request formulation change)
A 100 µg/ml solution in acetonitrile
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/ml
SMILES
CC(CC(C)C)NC1=CC(C(NC2=CC=CC=C2)=CC1=O)=O
InChi Code
InChI=1S/C18H22N2O2/c1-12(2)9-13(3)19-15-10-18(22)16(11-17(15)21)20-14-7-5-4-6-8-14/h4-8,10-13,19-20H,9H2,1-3H3
InChi Key
UBMGKRIXKUIXFQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 µg

    $49

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    Cayman Chemical
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    Product Description

    6-PPD-Q (solution) is a substituted p-phenylenediamine (PPD) quinone, oxidized transformation product of the tire rubber antioxidant 6-PPD (Item No. 38246), and an environmental toxicant.1 This product is supplied in an amber ampule in which the headspace has been purged with argon. 6-PPD-Q has been detected as a contaminant in atmospheric particles, road dust, and various aquatic sources, including surface water, stormwater, and wastewater, among other media.1,2 6-PPD-Q is highly toxic to aquatic organisms, including salmon and zebrafish, and induces oxidative stress, DNA damage, inflammation, and reproductive dysfunction in model organisms.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, S., Tang, J., Qiu, Z., et al. Environmental and human health risks of 6PPD and 6PPDQ: Assessment and implications. Toxics 13(10), 873 (2025).

    2. Bohara, K., Timilsina, A., Adhikari, K., et al. A mini review on 6PPD quinone: A new threat to aquaculture and fisheries. Environ. Pollut. 340(Pt 2), 122828 (2024).