A PEGylated form of cholesterol
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Cholesterol-PEG(2000)-amine (hydrochloride)

Item No. 45631

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (2-(2-aminoethoxy)ethyl)carbamate, monohydrochloride
Molecular Formula
(C2H4O)nC30H52N2O2 • HCl
Formula Weight
553.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble: 0.1-1 mg/ml
SMILES
C[C@]12C(C[C@@H](OC(NCCOCCN)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C.Cl
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $98

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    50 mg

    $319

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    100 mg

    $539

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    Cayman Chemical
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    Product Description

    Cholesterol-PEG(2000)-amine is a PEGylated form of cholesterol (Item Nos. 9003100 | 39088). It has been used in the synthesis of conjugates containing cholesterol and pheophorbide a (Item No. 16072) for the formation of photosensitizing lipid nanoparticles (LNPs) with pro-oxidant and ferroptosis-inducing activity in cancer cells.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bae, G.H., Shin, S., Park, J.D., et al. Photosensitizing lipid nanoparticles for ferroptosis-enhanced photodynamic cancer therapy via GPX4 silencing. Adv. Healthc. Mater. 15(7), e03748 (2026).