A flavonoid glycoside with diverse biological activities
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Spiraeoside

Item No. 45667

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[4-(β-D-glucopyranosyloxy)-3-hydroxyphenyl]-3,5,7-trihydroxy-4H-1-benzopyran-4-one
CAS Number
20229-56-5
Synonyms
  • Quercetin-4-O-β-D-glycoside
  • Quercetin 4’-O-glucoside
Molecular Formula
C21H20O12
Formula Weight
464.4
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(O)=C(C=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C1O
InChi Code
InChI=1S/C21H20O12/c22-6-13-15(26)17(28)19(30)21(33-13)32-11-2-1-7(3-9(11)24)20-18(29)16(27)14-10(25)4-8(23)5-12(14)31-20/h1-5,13,15,17,19,21-26,28-30H,6H2/t13-,15-,17+,19-,21-/m1/s1
InChi Key
OIUBYZLTFSLSBY-HMGRVEAOSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $65

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    5 mg

    $293

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    10 mg

    $455

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    25 mg

    $975

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    Product Description

    Spiraeoside is a flavonoid glycoside that has been found in F. ulmaria and has diverse biological activities.1,2 It scavenges DPPH (Item No. 14805) and hydroxyl radicals (IC50s = 19.54 and 5.1 µg/ml, respectively) and inhibits β-glucuronidase and lipoxygenase (LO) in cell-free assays. Spiraeoside (15 µg/ml) induces cell cycle arrest and apoptosis in HeLa cervical cancer cells.2 It decreases the severity of ethanol-induced gastric lesions in rats when administered at a dose of 50 mg/kg.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Samardžić, S., Arsenijević, J., Božić, D., et al. Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench. J. Ethnopharmacol. 213, 132-137 (2018).

    2. Nile, A., Nile, S.H., Cespedes-Acuña, C.L., et al. Spiraeoside extracted from red onion skin ameliorates apoptosis and exerts potent antitumor, antioxidant and enzyme inhibitory effects. Food Chem. Toxicol. 154, 112327 (2021).