An internal standard for the quantification of 11-deoxy cortisol
Related Products
Unlabeled Version(s)
2077511-deoxy Cortisol
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

11-deoxy Cortisol-d2

Item No. 45693

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
17,21-dihydroxy-pregn-4-ene-3,20-dione-21,21-d2
CAS Number
1271728-08-5
Synonyms
  • Compound S-d2
  • Cortexolone-d2
  • Cortodoxone-d2
  • Reichstein’s Substance S-d2
Molecular Formula
C21H28D2O4
Formula Weight
348.5
Purity
≥99% deuterated forms (d1-d2)
Formulation (Request formulation change)
A 1 mg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(C([2H])([2H])O)=O)=C1
InChi Code
InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1/i12D2
InChi Key
WHBHBVVOGNECLV-FAWVBKBISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $395

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    11-deoxy Cortisol-d2 is intended for use as an internal standard for the quantification of 11-deoxy cortisol by GC- or LC-MS. 11-deoxy Cortisol is a precursor in the biosynthesis of cortisol (Item No. 20739).1 It is converted into cortisol by the cytochrome P450 (CYP) isoform CYP11B1, also known as 11β-hydroxylase. Urinary levels of 11-deoxy cortisol and the ratio of 11-deoxy cortisol to cortisol are elevated in patients with 11β-hydroxylase deficiency, a type of congenital adrenal hyperplasia (CAH) characterized by cortisol deficiency and hypertension.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Keavney, B., Mayosi, B., Gaukrodger, N., et al. Genetic variation at the locus encompassing 11-β hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion. J. Clin. Endocrinol. Metab. 90(2), 1072-1077 (2005).