A flavonol glycoside with diverse biological activities
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Catechin 7-O-β-D-Glucopyranoside

Item No. 45760

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5-dihydroxy-2H-1-benzopyran-7-yl β-D-glucopyranoside
CAS Number
65597-47-9
Molecular Formula
C21H24O11
Formula Weight
452.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O[C@H]1[C@H](OC(C=C2O[C@@H]3C4=CC(O)=C(O)C=C4)=CC(O)=C2C[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChi Code
InChI=1S/C21H24O11/c22-7-16-17(27)18(28)19(29)21(32-16)30-9-4-12(24)10-6-14(26)20(31-15(10)5-9)8-1-2-11(23)13(25)3-8/h1-5,14,16-29H,6-7H2/t14-,16+,17+,18-,19+,20+,21+/m0/s1
InChi Key
VLFIBROLAXKPQK-DPRDWZRASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $55

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    5 mg

    $165

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    10 mg

    $248

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    25 mg

    $550

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    Cayman Chemical
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    Product Description

    Catechin 7-O-β-D-glucopyranoside is a flavonol glycoside that has been found in P. longifolia and has diverse biological activities.1,2,3 It inhibits lipid peroxidation and scavenges hydroxyl radicals and superoxide anions in cell-free assays in a concentration-dependent manner and inhibits hydrogen peroxide-induced DNA damage and apoptosis in BJAB B cell lymphoma cells at 200 µM.1 Catechin 7-O-β-D-glucopyranoside also inhibits lipid accumulation in 3T3-L1 cells.3 It decreases disease severity in a rat model of colitis at 2-10 mg/kg.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baek, J.A., Son, Y.-O., Fang, M., et al. Catechin-7-O-β-D-glucopyranoside scavenges free radicals and protects human B lymphoma BJAB cells on H₂O₂-mediated oxidative stress. Food Sci. Biotechnol. 20(1), 151-158 (2011).

    2. Wang, Z., Cui, Y., Xu, S., et al. Anti-lipid accumulation effects and mechanism of the extract and isolated compounds from Potentilla longifolia. Fitoterapia 168, 105524 (2023).

    3. Kook, S.-H., Choi, K.-C., Cho, S.-W., et al. Catechin-7-O-β-D-glucopyranoside isolated from the seed of Phaseolus calcaratus Roxburgh ameliorates experimental colitis in rat. Int. Immunopharmacol. 29(2), 521-527 (2015).