A BSA complex with adrenic acid
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BSA-Adrenate Polyunsaturated Fatty Acid Complex (1.67 mM)

Item No. 45953

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Bovine Serum Albumin-AdA
  • Bovine Serum Albumin-Adrenate
  • BSA-AdA
  • BSA-7(Z),10(Z),13(Z),16(Z)-Docosatetraenoic Acid
Formulation (Request formulation change)
1.67 mM Adrenate:0.8 mM BSA (2:1 adrenate:BSA) in 150 mM sodium chloride, pH 7.4
Origin
Animal/Bovine
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 ml

    $182

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    Product Description

    BSA-Adrenate Polyunsaturated Fatty Acid Complex (1.67 mM) is composed of adrenic acid (Item No. 90300) and fatty acid-free bovine serum albumin (BSA) at an approximately 2:1 molar ratio of adrenate:BSA. It was prepared under sterile conditions, then filtered and aliquoted into sterile vials. Cayman’s BSA-Adrenate Polyunsaturated Fatty Acid Complex (1.67 mM) can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring lipid metabolism and inflammatory signaling pathways.1,2 It can also be used to sensitize cells to ferroptosis via its incorporation into phosphatidylethanolamines (PEs) and subsequent oxidation to form pro-ferroptotic PE species.3 It is suitable for use in short- and long-term cell culture applications (25+ hours). For best results, it is recommended that this product be used in conjunction with Cayman’s BSA Control for BSA-Fatty Acid Complexes (5 mM) (Item No. 29556), prepared with fatty acid-free BSA.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Alsabeeh, N., Chausse, B., Kakimoto, P.A., et al. Cell culture models of fatty acid overload: Problems and solutions. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1863(2), 143-151 (2018).

    2. Brouwers, H., Jónasdóttir, H.S., Kuipers, M.E., et al. Anti-inflammatory and proresolving effects of the omega-6 polyunsaturated fatty acid adrenic acid. J. Immunol. 205(10), 2840-2849 (2020).

    3. Kagan, V.E., Mao, G., Qu, F., et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat. Chem. Biol. 13(1), 81-90 (2017).