A perfluoroalkyl substance
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Pentafluoropropionic Acid

Item No. 46061

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2,3,3,3-pentafluoro-propanoic acid
CAS Number
422-64-0
Synonyms
  • Perfluoropropionic Acid
  • PFPA
  • PFPrA
Molecular Formula
C3HF5O2
Formula Weight
164.0
Purity
≥98%
Formulation (Request formulation change)
A liquid
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble: ≥ 10 mg/ml
SMILES
O=C(C(F)(C(F)(F)F)F)O
InChi Code
InChI=1S/C3HF5O2/c4-2(5,1(9)10)3(6,7)8/h(H,9,10)
InChi Key
LRMSQVBRUNSOJL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

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    10 g

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    25 g

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    Product Description

    Pentafluoropropionic acid is a perfluoroalkyl substance (PFAS). It is a photocatalytic degradation product of perfluorooctanoic acid (PFOA; Item No. 37232) and has been found in tap and ground water.1,2 Pentafluoropropionic acid does not decrease the viability of mouse liver organoids.3 Formulations containing pentafluoropropionic acid have been used as ion pair reagents for liquid chromatography and mass spectrometry.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, F., Duan, J., Tian, S., et al. Short-chain per- and polyfluoroalkyl substances in aquatic systems: Occurrence, impacts and treatment. Chem. Eng. J. 380, 122506 (2020).

    2. Janda, J., Nödler, K., Brauch, H.-J., et al. Robust trace analysis of polar (C2-C8) perfluorinated carboxylic acids by liquid chromatography-tandem mass spectrometry: Method development and application to surface water, groundwater and drinking water. Environ. Sci. Pollut. Res. Int. 26(8), 7326-7336 (2019).

    3. Palazzolo, S., Caligiuri, I., Sfriso, A.A., et al. Early warnings by liver organoids on short- and long-chain PFAS toxicity. Toxics 10(2), 91 (2022).