An internal standard for the quantification of (S)-sulpiride
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(S)-Sulpiride-d3

Item No. 46110

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(S)-5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-(methoxy-d3)-benzamide
CAS Number
124020-27-5
Synonyms
  • Levosulpiride-d3
  • RV-12309-d3
  • (–)-Sulpiride-d3
  • (S)-(–)-Sulpiride-d3
Molecular Formula
C15H20D3N3O4S
Formula Weight
344.4
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
[2H]C([2H])([2H])OC(C=CC(S(N)(=O)=O)=C1)=C1C(NC[C@H]2N(CCC2)CC)=O
InChi Code
InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1/i2D3
InChi Key
BGRJTUBHPOOWDU-BINOJTDESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    (S)-Sulpiride-d3 is intended for use as an internal standard for the quantification of (S)-sulpiride by GC- or LC-MS. (S)-Sulpiride is a dopamine D2 receptor antagonist (Ki = 6.9 nM).1 It reduces apomorphine-induced locomotion in mice when administered at doses ranging from 4-64 mg/kg.2 Formulations containing (S)-sulpiride have been used in the treatment of schizophrenia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Högberg, T., Bengtsson, S., de Paulis, T., et al. Potential antipsychotic agents. 5. Synthesis and antidopaminergic properties of substituted 5,6-dimethoxysalicylamides and related compounds. J. Med. Chem. 33(4), 1155-1163 (1990).

    2. Jenner, P., Clow, A., Reavill, C., et al. Stereoselective actions of substituted benzamide drugs on cerebral dopamine mechanisms. J. Pharm. Pharmacol. 32, 39-44 (1980).