A triterpenoid saponin with antioxidant and lipid-lowering activities
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Soyasaponin Aa

Item No. 46118

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranosiduronic acid
CAS Number
117230-33-8
Synonyms
  • Acetylsoyasaponin A4
Molecular Formula
C64H100O31
Formula Weight
1365.5
Purity
≥98%
Formulation (Request formulation change)
A solid
SMILES
C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])CC(C)([C@H]([C@H]4O[C@H]5[C@@H]([C@H]([C@H](CO5)O)O[C@H]6[C@@H]([C@H]([C@@H](CO6)OC(C)=O)OC(C)=O)OC(C)=O)O)O)C)C)C)([H])[C@@]7([C@@]([C@](C)([C@H](CC7)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)C(O)=O)O)O)O[C@H]9[C@@H]([C@H]([C@H]([C@H](O9)CO)O)O)O[C@@H]%10O[C@@H]([C@H]([C@@H]([C@H]%10O)O)O)CO)CO)([H])CC1)C
InChi Code
InChI=1S/C64H100O31/c1-25(68)85-33-23-84-56(50(87-27(3)70)46(33)86-26(2)69)91-45-30(71)22-83-54(44(45)79)95-52-51(80)59(4,5)19-29-28-11-12-35-61(7)15-14-36(62(8,24-67)34(61)13-16-64(35,10)63(28,9)18-17-60(29,52)6)90-58-49(42(77)41(76)47(92-58)53(81)82)94-57-48(40(75)38(73)32(21-66)89-57)93-55-43(78)39(74)37(72)31(20-65)88-55/h11,29-52,54-58,65-67,71-80H,12-24H2,1-10H3,(H,81,82)/t29-,30-,31+,32+,33+,34+,35+,36-,37+,38-,39-,40-,41-,42-,43+,44+,45-,46-,47-,48+,49+,50+,51-,52+,54-,55-,56-,57-,58+,60+,61-,62+,63+,64+/m0/s1
InChi Key
KBGJRGWLUHSDLW-HCOXMXEYSA-N
Origin
Plant/Soybean
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Soyasaponin Aa is a triterpenoid saponin that has been found in G. max and has antioxidant and lipid-lowering activities.1,2 It reverses hydrogen peroxide-induced increases in malondialdehyde (MDA) levels and decreases in superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) activities in HepG2 cells at 100 µg/ml.1 Soyasaponin Aa (100 µM) inhibits peroxisome proliferator-activated receptor γ (PPARγ) transactivation in a reporter assay using HEK293T cells and decreases lipid accumulation in 3T3-L1 adipocytes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhu, L., Zhang, M., Liu, X., et al. Evaluation of in vitro antioxidant activities of soyasaponins from soy hypocotyls in human HepG2 cell line. Chem. Pap. 71, 653–660 (2017).

    2. Yang, S.H., Ahn, E.-K., Lee, J.A., et al. Soyasaponins Aa and Ab exert an anti-obesity effect in 3T3-L1 adipocytes through downregulation of PPARγ. Phytother. Res. 29(2), 281-287 (2015).