A β2-AR agonist
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Clenproperol

Item No. 46198

Technical Information
Formal Name
4-amino-3,5-dichloro-α-[[(1-methylethyl)amino]methyl]-benzenemethanol
CAS Number
38339-11-6
Molecular Formula
C11H16Cl2N2O
Formula Weight
Purity
≥98%
A solid
DMSO: Soluble: ≥10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
ClC1=C(N)C(Cl)=CC(C(CNC(C)C)O)=C1
InChi Code
InChI=1S/C11H16Cl2N2O/c1-6(2)15-5-10(16)7-3-8(12)11(14)9(13)4-7/h3-4,6,10,15-16H,5,14H2,1-2H3
InChi Key
JXUDZCJTCKCTQK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Clenproperol is an agonist of the β2-adrenergic receptor (β2-AR).1,2 It is commonly included as a standard alongside the β2-AR agonist clenbuterol (Item No. 14985) in the analysis of potential contaminants in livestock meat, feed, or water.3,2 Clenproperol has been found in a commercially available porcine liver sample.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Casella, I., Ambrosio, C., Grò, M.C., et al. Divergent agonist selectivity in activating beta1- and beta2-adrenoceptors for G-protein and arrestin coupling. Biochem. J. 438(1), 191-202 (2011).

    2. Ramos, F., Baeta, M.L., Reis, J., et al. Evaluation of the illegal use of clenbuterol in Portuguese cattle farms from drinking water, urine, hair and feed samples. Food Addit. Contam. Part A Chem. Anal. Control Expo. Risk Assess. 26(6), 814-820 (2009).

    3. Shao, B., Jia, X., Zhang, J., et al. Multi-residual analysis of 16 β-agonists in pig liver, kidney and muscle by ultra performance liquid chromatography tandem mass spectrometry. Food Chem. 114(3), 1115-1121 (2009).