For the quantification of RvD1
Features
  • Detect RvD1 in multiple sample types
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure RvD1 levels down to 15 pg/ml
  • Incubation: 18 hours | Development: 90-120 minutes | Read: Colorimetric at 405-420 nm
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Resolvin D1 ELISA Kit

Item No. 500380

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Resolvin D1 EIA Kit
  • 17(S)-Resolvin D1
  • RvD1
Assay Range
3.3-2,000 pg/ml
Sensitivity
80% B/B0: 15 pg/ml
Cross Reactivity
(5(S),6(R)-Lipoxin A4) 20%(17(R)-Resolvin D1) 4.2%(10(S),17(S)-DiHDoHE) 0.7%(Resolvin D2) 0.05%(Docosahexaenoic Acid) <0.01%(17(R)-HDoHE) <0.01%(17(S)-HDoHE) <0.01%(17(S)-HpDoHE) <0.01%(Resolvin E1) <0.01%
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    Resolvin D1 ELISA Kit Notice

    Please read the following carefully before purchasing this assay.

    In light of the ongoing discussions on the detection of specialized pro-resolving mediators (SPMs) in the scientific community, researchers are advised to validate results from this ELISA with a secondary detection method or to clearly report the limitations of this ELISA in their publications.

    READ THE FULL NOTICE
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    Product Description

    Cayman’s Resolvin D1 (RvD1) ELISA Kit is a competitive assay that can be used for quantification of RvD1 (17(S)-Resolvin D1) in plasma, serum, and cell culture supernatants. The assay has a range from 3.3-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 15 pg/ml.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Li, J., Xiao, Y., Zhang, Y., et al. Pulmonary delivery of specialized pro-resolving mediators-based nanotherapeutics attenuates pulmonary fibrosis in preclinical animal models. ACS Nano 17(16), 15354-15370 (2023).

    Recchiuti, A., Patruno, S., Mattoscio, D., et al. Resolvin D1 and D2 reduce SARS-CoV-2-induced inflammatory responses in cystic fibrosis macrophages. The FASEB Journal 35(4), e21441 (2021).

    Perucci, L.O., Santos, T.A.P., Santos, P.C., et al. Pre-eclampsia is associated with reduced resolvin D1 and maresin 1 to leukotriene B4 ratios in the plasma. Am. J. Reprod. Immunol. 83, e13206 (2020).

    Krashia, P., Cordella, A., Nobili, A., et al. Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson’s disease. Nat. Commun. 10, 4725 (2019).

    Bisicchia, E., Sasso, V., Catanzaro, G., et al. Resolvin D1 halts remote neuroinflammation and improves functional recovery after focal brain damage via ALX/FPR2 receptor-regulated microRNAs. Mol. Neurobiol. 55(8), 6894-6905 (2018).

    Navarini, L., Bisogno, T., Margiotta, D.P.E., et al. Role of the specialized proresolving mediator resolvin D1 in systemic lupus erythematosus: Preliminary results. J. Immunol. Res. 2018(5264195), (2018).