For the quantification of MaR1
Features
  • Detect MaR1 in human urine
  • Assay 24 samples in triplicate or 36 samples in duplicate
  • Measure MaR1 levels down to 6 pg/ml
  • Incubation: 18 hours | Development: 90-120 minutes | Read: Colorimetric at 405-420 nm
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Maresin 1 ELISA Kit

Item No. 501150

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • MaR1
  • 7(R)-MaR1
  • 7(R)-Maresin 1 EIA Kit
Limit of Detection
5.8 pg/ml
Assay Range
7.8-1,000 pg/ml
Sensitivity
15 pg/ml
Cross Reactivity
(MaR1) 100%(7-epi MaR1) 46%(DHA) <0.01%(14S-HDHA) <0.01%(17R-HDHA) <0.01%(17S-HDHA) <0.01%(10S,17S-diHDHA) <0.01%(LTB4) <0.01%(LXA4) <0.01%(15-epi LXA4) <0.01%(LXA5) <0.01%(LXB4) <0.01%(RvD1) <0.01%(17R-RvD1) <0.01%(RvD2) <0.01%(RvD3) <0.01%(RvE1) <0.01%
Origin
Animal/Bovine, Animal/Eel, Animal/Rabbit
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    96 solid wells

    $512

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    96 strip wells

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    Maresin 1 ELISA Kit Notice

    Please read the following carefully before purchasing this assay.

    In light of the ongoing discussions on the detection of specialized pro-resolving mediators (SPMs) in the scientific community, researchers are advised to validate results from this ELISA with a secondary detection method or to clearly report the limitations of this ELISA in their publications.

    READ THE FULL NOTICE
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    Product Description

    Maresins (macrophage mediators in resolving inflammation) are members of a class of potent anti-inflammatory and pro-resolving mediators that are synthesized by macrophages in the presence of docosahexaenoic acid (DHA). Maresin 1 (MaR1) is produced via oxidation of endogenous DHA by 12-lipoxygenase. MaR1 has been shown to reduce neutrophil infiltration in murine peritonitis, enhance efferocytosis, inhibit TRPV1 currents in neurons, reduce neuropathic pain in mice, and attenuate disease severity in mouse models of colitis. Although circulating levels of MaR1 may be quite low, MaR1 can be detected in urine.

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Yavuz, A., Ugur, K., Karaca Karagoz, Z., et al. Blood, saliva and urine maresin-1 and malondialdehyde may be useful biomarker in patients with polycystic ovary syndrome: A prospective study. Clin. Exp. Obstet. Gynecol. 49(4), 87 (2022).

    Perucci, L.O., Santos, T.A.P., Santos, P.C., et al. Pre-eclampsia is associated with reduced resolvin D1 and maresin 1 to leukotriene B4 ratios in the plasma. Am. J. Reprod. Immunol. 83, e13206 (2020).