Glucose Uptake Cell-Based Assay Kit | Cayman Chemical
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Glucose Uptake Cell-Based Assay Kit

Item № 600470
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SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 ea $250.00 0.00

Pricing updated 2018-08-15. Prices are subject to change without notice.

Description
Features
  • Used for the direct detection of glucose taken up in cells using the fluorescently-labeled deoxyglucose analog 2-NBDG
  • Flexible format can be analyzed with either flow cytometry or fluorescence plate reader
  • Utilizes buffers compatible with Western blot, allowing subsequent testing of intact cells
  • Apigenin (Item No. 10010275) a flavinoid and a known inhibitor of glucose transport is included as a control

Glucose metabolism is a primary source of energy and biomaterials for the maintenance of cell homeostasis. Extra glucose is stored in the muscles and liver as glycogen which is hydrolyzed to glucose and released into the blood when needed. The rate of glucose uptake in cells is dynamic and tightly regulated by hormones and/or growth factors including insulin. Cancer cells exhibit increased glucose uptake and metabolism by aerobic glycolysis in order to support a high rate of proliferation. Chemicals that block glucose uptake by cancer cells have been shown to have anti-cancer effects. Cayman’s Glucose Uptake Cell-based Assay Kit provides a convenient tool for studying modulators of cellular glucose uptake. The kit employs 2-NBDG, a fluorescently-labeled deoxyglucose analog, as a probe for the detection of glucose taken up by cultured cells. Apigenin, a flavonoid that has been reported to be an inhibitor of glucose transport, is included as a control.

Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

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Technical Information

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
Downloads & Resources
Product Downloads

Download Kit Booklet

Download Safety Data Sheet (SDS)

Download free InChI Key generation software

Additional Information

View the Cayman Structure Database for chemical structure definitions for many Cayman products

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Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data pack, and GC-MS data.

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You may be eligible to receive a free sample of Glucose Uptake Cell-Based Assay Kit under the Cayman Challenge program.

Cayman Chemical

1180 East Ellsworth Road

Ann Arbor, Michigan 48108 USA

Toll Free: (800) 364-9897

(USA and Canada Only)

Fax: (734) 971-3640