A PAF receptor antagonist
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(±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane

Item No. 60950

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,4R)-rel-2,4-bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane
CAS Number
116673-45-1
Synonyms
  • trans-BTP Dioxolane
Molecular Formula
C21H26O8
Formula Weight
406.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlDMSO:PBS (1:10): 0.1 mg/mlDMSO:PBS (1:3): 2.5 mg/mlEthanol: 35 mg/ml
SMILES
COC1=CC([C@H]2O[C@H](C3=CC(OC)=C(OC)C(OC)=C3)OC2)=CC(OC)=C1OC
InChi Code
InChI=1S/C21H26O8/c1-22-14-7-12(8-15(23-2)19(14)26-5)18-11-28-21(29-18)13-9-16(24-3)20(27-6)17(10-13)25-4/h7-10,18,21H,11H2,1-6H3/t18-,21+/m0/s1
InChi Key
DUAYHYGJMLZLCE-GHTZIAJQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    trans-BTP Dioxolane is a PAF receptor antagonist. This compound demonstrates competitive antagonism of PAF in a rabbit washed platelet assay (Ki = 0.3 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Corey, E.J., Chen, C.P., and Parry, M.J. Dual binding modes to the receptor for platelet activating factor (PAF) of anti-PAF trans-2,5-diarylfurans. Tetrahedron Lett. 29(24), 2899-2902 (1988).