For the measurement of creatinine levels in plasma and serum
Features
  • Measure creatinine levels in plasma and serum
  • Assay 40 samples in duplicate
  • Measure creatinine levels down to 0.5 mg/dl
  • Plate-based colorimetric measurement (490-500 nm)
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Creatinine (serum) Colorimetric Assay Kit

Item No. 700460

Kit Booklet (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Limit of Detection
0.5 mg/dl
Lower Limit of Quantification
1 mg/dl
Shipping & Storage Information
Storage
4°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    2 x 96 wells

    $285

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    Cayman Chemical
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    Product Description

    Cayman’s Creatinine (serum) Colorimetric Assay can be used to measure creatinine levels in plasma and serum. The assay relies on the Jaffe’ reaction, wherein a yellow/orange color forms when the metabolite is treated with alkaline picrate.2 The rate of color development is directly proportional to the concentration of creatinine in the sample and is measured at an absorbance between 490-500 nm. The kinetic nature of the assay eliminates interference from extraneous serum contaminants, such as lipids and bilirubin.1,2

    Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bowers, L.D., and Wong, E.T. Kinetic serum creatinine assays. II. A critical evaluation and review. Clin. Chem. 26(5), 555-561 (1980).

    2. Bowers, L.D. Kinetic serum creatinine assays I. The role of various factors in determining specificity. Clin. Chem. 26(5), 551-554 (1980).

    Product Citations

    Ontawong, A., Nehra, G., Maloney, B.J., et al. N-acetylcysteine attenuates Aβ-mediated oxidative stress, blood-brain barrier leakage, and renal dysfunction in 5xFAD mice. Int. J. Mol. Sci. 26(9), 4352 (2025).

    Grant, M.K.O., Seelig, D.M., Sharkey, L.C., et al. Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice. PLoS One 14(2), e0212486 (2019).

    Yu, S.-H., Dubey, N.K., Li, W.-S., et al. Cordyceps militaris treatment preserves renal function in type 2 diabetic nephropathy mice. PLoS One 11(11), e0166342 (2016).

    Antolic, A., Feng, X., Wood, C.E., et al. Increased maternal nighttime cortisol concentrations in late gestation alter glucose and insulin in the neonatal lamb. Physiol. Rep. 3(9), e12548 (2015).

    Yokogawa, M., Takaishi, M., Nakajima, K., et al. Epicutaneous application of toll-like receptor 7 agonists leads to systemic autoimmunity in wild-type mice: A new model of systemic Lupus erythematosus. Arthirits Rheumatol. 66(3), 694-706 (2014).

    Claybaugh, T., Decker, S.J., McCall, K., et al. L-Arginine supplementation in type II diabetic rats preserves renal function and improves insulin sensitivity by altering the nitric oxide pathway. Int. J. Endocrinol. 171546 (2014).