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Cayman’s LipidLaunch™ ALC-0315 LNP Kit (Loadable) provides cargo-ready, empty ALC-0315 LNPs. These LNPs are capable of rapid encapsulation of nucleic acids, without the need for incubation steps, enabling subsequent delivery to target cells or other downstream research applications. LipidLaunch™ LNPs (Loadable) demonstrate very low toxicity compared to traditional lipid-based transfection methods.
Conventionally loaded LNPs typically require specialized equipment to ensure consistent control of particle size, while also requiring large reaction volumes. LipidLaunch™ ALC-0315 LNPs (Loadable) enable users to encapsulate cargo in low reaction volumes offering greater flexibility in the scale of preparation while preserving costly nucleic acid cargo.
LipidLaunch™ ALC-0315 LNP (Loadable) performance is dependent on a variety of factors, including cargo type and cell line, so optimization of these parameters is necessary. To aid in optimization, consider using Cayman’s LipidLaunch™ LNP Screening Set (Loadable) (Item No. 502868) or LipidLaunch™ ALC-0315 LNPs preloaded with mCherry, luciferase, or GFP mRNA (Item Nos. 40103 | 40104 | 40105).
WARNING This product is not for human or veterinary use.