An inhibitor of FAAH
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Arachidonoyl Serotonin

Item No. 70665

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide
CAS Number
187947-37-1
Synonyms
  • AA-5HT
Molecular Formula
C30H42N2O2
Formula Weight
462.7
Purity
≥98%
Formulation
A 50 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >30 mg/mlDMSO: >15 mg/mlEthanol: >30 mg/mlPBS pH 7.2: >290 µg/ml
λmax
223, 278 nm
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCc1c[nH]c2ccc(O)cc12
InChi Code
InChI=1S/C30H42N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-30(34)31-23-22-26-25-32-29-21-20-27(33)24-28(26)29/h6-7,9-10,12-13,15-16,20-21,24-25,32-33H,2-5,8,11,14,17-19,22-23H2,1H3,(H,31,34)/b7-6-,10-9-,13-12-,16-15-
InChi Key
QJDNHGXNNRLIGA-DOFZRALJSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $54

    Add

    10 mg

    $91

    Add

    50 mg

    $341

    Add

    100 mg

    $627

    Add
    Cannabinoid Resource Center
    Discover Our Tools to Support Cannabinoid Research and Analysis.
    • Cannabinoid signaling research products
    • Analytical standards and certified reference materials
    • Endocannabinoid profiling services
    • Lab wall posters
    • Articles, application notes, and webinars
    LEARN MORE
    Product Description

    Arachidonoyl serotonin is an inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of anandamide and other endogenous cannabinoids. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 µM. Both the Km and the Vmax of the enzyme are affected, indicating the Arachidonoyl serotonin is a very tight binding, competitive inhibitor of FAAH. Arachidonoyl serotonin does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bisogno, T., Melck, D., De Petrocellis, L., et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochem. Biophys. Res. Commun. 248(3), 515-522 (1998).