A substrate for nitric oxide synthase
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L-hydroxy Arginine (acetate)

Item No. 80300

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N5-[(hydroxyamino)iminomethyl]-L-ornithine, acetate
CAS Number
53598-01-9
Synonyms
  • L-NG-hydroxy Arginine
  • N5-hydroxy L-Arginine
  • Nω-hydroxy-L-Arginine
Molecular Formula
C6H14N4O3 • XC2H4O2
Formula Weight
190.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: Slightly solubleDMSO: Slightly solubleEthanol: Slightly solublePBS pH 7.2: 20 mg/ml
SMILES
N=C(NCCC[C@H](N)C(O)=O)NO.CC(O)=O
InChi Code
InChI=1S/C6H14N4O3.C2H4O2/c7-4(5(11)12)2-1-3-9-6(8)10-13;1-2(3)4/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10);1H3,(H,3,4)
InChi Key
VYMCYRPQICLHKC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $108

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    10 mg

    $195

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    25 mg

    $428

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    50 mg

    $748

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    Cayman Chemical
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    Product Description

    L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine (Item No. 23703) to form nitric oxide.1 It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Knowles, R.G., and Moncada, S. Nitric oxide synthases in mammals. Biochem. J. 298, 249-258 (1994).

    2. Garlichs, C.D., Beyer, J., Zhang, H., et al. Decreased plasma concentrations of L-hydroxy-arginine as a marker of reduced NO formation in patients with combined cardiovascular risk factors. J. Lab. Clin. Med. 135(5), 419-425 (2000).